In this study, the Laplace Adomian decomposition technique (LADT) is employed to analyse a numerical study with the SDIQR mathematical model of COVID-19 for infected migrants in Odisha. The analytical power series and LADT are applied to the Covid-19 model to estimate the solution profiles of the dynamical variables. We proposed a mathematical model that incorporates both the resistive class and the quarantine class of COVID-19. We also introduce a procedure to evaluate and control the infectious disease of COVID-19 through the SDIQR pandemic model. Five compartments like susceptible ( S ), diagnosed ( D ), infected ( I ), quarantined ( Q ) and recovered ( R ) population are found in our model. The model can only be solved approximately rather than analytically as it contains a system of nonlinear differential equations with reaction rates. To demonstrate and validate our model, the numerical simulations for infected migrants are plotted with suitable parameters.