Survival After Induction Chemotherapy and Chemoradiation Versus Chemoradiation and Adjuvant Chemotherapy for Locally Advanced Rectal Cancer.
Jin K KimMichael R MarcoCampbell S D RoxburghChin-Tung ChenAndrea CercekPaul StrombomLarissa K F TempleGarrett M NashJose G GuillemPhilip B PatyRona YaegerZsofia K StadlerMithat GonenNeil H SegalDiane L ReidyAnna VargheseJinru ShiaEfsevia VakianiAbraham J WuPaul B RomesserChristopher H CraneMarc J GollubLeonard SaltzJ Joshua SmithMartin R WeiserSujata PatilJulio Garcia-AguilarPublished in: The oncologist (2022)
Although TNT does not prolong survival than neoadjuvant chemoradiotherapy plus intended postoperative chemotherapy, the higher response rate associated with TNT may create opportunities to preserve the rectum in more patients with LARC.