DNA methylation patterns of RAR-β2 and RASSF1A gene promoters in FNAB samples from Greek population with benign or malignant breast lesions.

Niki KougioumtsidouEleftherios VavoulidisMaria NasioutzikiMarianthi SymeonidouGeorgios Chrysostomos PratilasEvangelia MaretiStamatios PetousisAnthoula ChatzikyriakidouGregorios GrimbizisTheodoros TheodoridisDimosthenis MiliarasKonstantinos DinasLeonidas Zepiridis

Published in: Diagnostic cytopathology (2020)

To optimize the sensitivity and specificity of this epigenetic setting, more TSGs related to BC should be gradually imported in our evaluated methylation panel and be validated in a larger study sample with the aim that the obtained epigenetic profiles will provide clinicians with valuable tools for management of BC patients in Greece.

Keyphrases

dna methylation
genome wide
gene expression
end stage renal disease
ejection fraction
copy number
chronic kidney disease
peritoneal dialysis
prognostic factors
transcription factor
patient reported outcomes
genome wide identification