Proteomic analysis of serum biomarkers for prediabetes using the Long-Evans Agouti rat, a spontaneous animal model of type 2 diabetes mellitus.

Eri TakahashiHiroyuki Unoki-KubotaYukiko ShimizuTadashi OkamuraWakiko IwataHiroshi KajioRitsuko Yamamoto-HondaTomoko ShigaShigeo YamashitaKazuyuki TobeAkinori OkumuraMichihiro MatsumotoKazuki YasudaMitsuhiko NodaYasushi Kaburagi

Published in: Journal of diabetes investigation (2017)

These findings suggest a possible role for SERPINA3 in the development of the early stages of type 2 diabetes mellitus, although further replication studies and functional investigations regarding their role are required.

Keyphrases

oxidative stress