Genomic characterization of triple-carbapenemase-producing Acinetobacter baumannii .
Ken-Ichi OinumaMasato SuzukiArata SakiyamaTaishi TsubouchiKozo SaekiKanako SatoMamiko NikiKoichi YamadaKeigo ShibayamaHiroshi KakeyaYukihiro KanekoPublished in: JAC-antimicrobial resistance (2021)
Our data revealed the genomic organization of OCU_Ac16a and demonstrated that all the carbapenemase genes are functional, each contributing to the extremely high broad-spectrum resistance of OCU_Ac16a to β-lactams. As multiple-carbapenemase producers can be serious health threats as drug-resistant pathogens and disseminators of carbapenemase genes, close attention should be paid to their emergence.
Keyphrases
- acinetobacter baumannii
- drug resistant
- multidrug resistant
- gram negative
- pseudomonas aeruginosa
- klebsiella pneumoniae
- genome wide
- public health
- copy number
- healthcare
- working memory
- bioinformatics analysis
- mental health
- electronic health record
- escherichia coli
- gene expression
- single cell
- dna methylation
- genome wide identification
- transcription factor
- deep learning