Differences in brain structure and function in children with the FTO obesity-risk allele.

Claudia Lugo-CandelasYajing PangSeonjoo LeeJiook ChaSusie HongLisa M RanzenhoferRachel KornHaley DavisHailey McInernyJanet SchebendachWendy K ChungRudolph L LeibelB Timothy WalshJonathan PosnerMichael RosenbaumLaurel Mayer

Published in: Obesity science & practice (2020)

This is the first study to examine brain structure and function related to FTO alleles in young children not yet manifesting obesity. This study lends support to the notion that the cerebellum may be involved in FTO-related risk for obesity, yet replication and further longitudinal study are required.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
type diabetes
high fat diet induced
resting state
white matter
young adults
adipose tissue
skeletal muscle
functional connectivity
multiple sclerosis
physical activity