Large multicenter randomized trials in autism: key insights gained from the balovaptan clinical development program.

Suma Jacob Evdokia Anagnostou Eric Hollander Roger Jou Nora McNamara Linmarie Sikich Russell H Tobe Declan G M Murphy James T McCracken Elizabeth Ashford Christopher Chatham Susanne Clinch Janice Smith Kevin Sanders Lorraine Murtagh Jana Noeldeke Jeremy Veenstra-VanderWeele

Published in: Molecular autism (2022)

Taken together, the balovaptan clinical development program has advanced our understanding of the key challenges facing ASD treatment research. The insights gained can be used to inform and improve the design of future clinical trials with the collective aim of developing efficacious therapies to support individuals with ASD.

Keyphrases

autism spectrum disorder
clinical trial
intellectual disability
quality improvement
attention deficit hyperactivity disorder
double blind
replacement therapy
phase iii