A meta-epidemiological study on the reported treatment effect of pregabalin in neuropathic pain trials over time.
Emma T L ChengMohammad Cheik-HusseinNoelle LinAdriane M LewinJames H McAuleyIan A HarrisPublished in: PloS one (2023)
The reported treatment effect or analgesic efficacy of pregabalin from clinical trials has diminished over time. Clinical recommendations may need to be re-evaluated to account for recent evidence and to consider whether pregabalin therapy is indicated.