An epicutaneous therapeutic pollen-allergen extract delivery system in an allergic rhinitis mouse model: based on allergen loading on DC-specific aptamers conjugated nanogolds.

Safoora PordelNavideh HaghnavazMohammadAli RezaeeSaeideh Sadat ShobeiriBahareh AnsariMohammadreza DashtiMalihe MoghadamMotahare KhorramiMojtaba Sankian

Published in: Immunologic research (2023)

Loading total protein extract on the GNPs and the Apt-modified GNPs could be an effective approach to improve EPIT efficacy in a pollen-induced allergic mouse model.

Keyphrases

allergic rhinitis
mouse model
oxidative stress
diabetic rats
high glucose
anti inflammatory
dendritic cells
photodynamic therapy
protein protein
drug induced
amino acid
immune response
binding protein
small molecule