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Maternal separation affects the electrophysiological properties of Aδ-fibres and nociceptive behaviours in male and female mice.

Nancy PaniaguaRocío GirónCarlos Goicoechea GarcíaMª Isabel Martín-FontellesAna Bagues
Published in: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience (2020)
Although MS increases the activity and the mechanosensitivity of cutaneous Aδ-afferent fibres at both short and long periods of separation, only the longer interval of time induces nociceptive sensitivity alterations during adulthood. These results highlight the possible influence of a stress free environment during childhood to reduce nociceptive alterations in adulthood.
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