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Alterations in the small intestinal wall and motor function after repeated cisplatin in rat.

J A UrangaJ M García-MartínezC García-JiménezG VeraM I Martín-FontellesRaquel Abalo
Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2017)
Repeated cisplatin induces relatively long-lasting gut dysmotility in rat associated with important histopathological and molecular alterations in the small intestinal wall. In cancer survivors, the possible chemotherapy-induced histopathological, molecular, and functional intestinal sequelae should be evaluated.
Keyphrases
  • chemotherapy induced
  • oxidative stress
  • young adults
  • single molecule