Genetic polymorphisms associated with psoriasis and development of psoriatic arthritis in patients with psoriasis.

Nikolai Dyrberg LoftLone SkovMads Kirchheiner RasmussenRobert GniadeckiTomas Norman DamIvan BrandslundHans Jürgen HoffmannMalene Rohr AndersenRam Benny DessauAnn Christina BergmannNiels Møller AndersenMikkel Kramme AbildtoftPaal Skytt AndersenMerete Lund HetlandBente GlintborgSteffen BankUlla VogelVibeke Andersen

Published in: PloS one (2018)

Among a cohort of Danish patients with moderate-to-severe psoriasis, two SNPs in the IL12B and TNF genes were associated with susceptibility of psoriasis. None of the SNPs were specifically associated with isolated cutaneous psoriasis or psoriatic arthritis.

Keyphrases

genome wide
atopic dermatitis
rheumatoid arthritis
dna methylation
high intensity
genome wide analysis