Nickel-Catalyzed Kumada Cross-Coupling Reactions of Benzylic Sulfonamides.

Kirsten A HewittClaire A HerbertAlissa C Matus Elizabeth R Jarvo

Published in: Molecules (Basel, Switzerland) (2021)

Herein, we report a Kumada cross-coupling reaction of benzylic sulfonamides. The scope of the transformation includes acyclic and cyclic sulfonamide precursors that cleanly produce highly substituted acyclic fragments. Preliminary data are consistent with a stereospecific mechanism that allows for a diastereoselective reaction.

Keyphrases

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