Cai's herbal tea enhances mitochondrial autophagy of type 1 diabetic mellitus β cells through the AMPK/mTOR pathway and alleviates inflammatory response.
Hongchun LiYanfei GaoMengdi LiYue DongJie ChenBingyue ZhangKaiqiang LiYuqun CaiPublished in: Acta diabetologica (2024)
Cai's Herbal Tea exhibits significant therapeutic efficacy in T1DM mice by improving mitochondrial health and inducing autophagy through the AMPK-mTOR pathway in pancreatic islet β-cells. These findings highlight its potential as a therapeutic approach for T1DM management.
Keyphrases
- induced apoptosis
- oxidative stress
- endoplasmic reticulum stress
- inflammatory response
- cell cycle arrest
- cell death
- signaling pathway
- cell proliferation
- skeletal muscle
- public health
- type diabetes
- mental health
- toll like receptor
- mouse model
- health information
- lipopolysaccharide induced
- social media
- insulin resistance
- human health