Percutaneous Image-Guided Vertebral Fixation in Cancer-Related Vertebral Compression Fractures: A Case Series Study.
François H CornelisLeo RazakamanantsoaMohamed Ben AmmarMilan NajdawiFrancois GardavaudSanaa El-MouhadiMatthias BarralPublished in: Medicina (Kaunas, Lithuania) (2021)
Background and objectives: Cancer-related vertebral compression fractures (VCF) may cause debilitating back pain and instability, affecting the quality of life of cancer patients. To further drive cement deposition during vertebroplasty, the aims of this restrospective case series study were to report the feasibility, safety and short term efficacy (≤6 months) of percutaneous vertebral fixation in cancer-related vertebral compression fractures using various intravertebral implants. Methods: All consecutive cancer patients treated with percutaneous vertebral fixation for VCF were retrospectively included. Various devices were inserted percutaneously under image guidance and filled by cement. Descriptive statistics were used and a matched paired analysis of pain scores was performed to assess for changes following interventions. Results: A total of 18 consecutive patients (12 women (66.6%) and 6 men (33.3%); mean age 59.7 ± 15.5 years) were included. A total of 42 devices were inserted in 8 thoracic and 16 lumbar vertebrae. Visual analogue scale measurement significantly improved from 5.6 ± 1.8 preoperatively to 1.5 ± 1.7 at 1 week (p < 0.01) and to 1.5 ± 1.3 at 6 months (p < 0.01). No severe adverse events were observed, but three adjacent fractures occurred between 1 week and 5 months after implantation. Conclusions: Percutaneous vertebral fixation of cancer-related VCF is feasible and safe and allows pain relief.
Keyphrases
- minimally invasive
- bone mineral density
- ultrasound guided
- end stage renal disease
- postmenopausal women
- pain management
- newly diagnosed
- chronic kidney disease
- radiofrequency ablation
- physical activity
- squamous cell carcinoma
- clinical trial
- spinal cord
- polycystic ovary syndrome
- early onset
- type diabetes
- peritoneal dialysis
- metabolic syndrome
- prognostic factors
- adipose tissue
- deep learning
- pregnant women
- young adults
- insulin resistance
- spinal cord injury
- drug induced
- study protocol