Bacteriophages isolated from mouse feces attenuates pneumonia mice caused by Pseudomonas aeruginosa.
Nuttawut SutnuWiwat ChancharoenthanaSupitcha KamolratanakulPornpimol PhuengmaungUthaibhorn Singkham-InChiratchaya ChongrakSirikan MontathipDhammika Leshan WannigamaTanittha ChatsuwanPuey OunjaiMarcus J SchultzAsada LeelahavanichkulPublished in: PloS one (2024)
The phages attenuate pneumonia partly through an enhanced neutrophil bactericidal activity, but not via inducing NETs formation. The isolation of phages from the infected hosts themselves might be practically useful for future treatment. More studies are warranted.