A Macrophage-Related Gene Signature for Identifying COPD Based on Bioinformatics and ex vivo Experiments.

Zheming ZhangHaoda YuQi WangYu DingZiteng WangSongyun ZhaoTao Bian

Published in: Journal of inflammation research (2023)

According to the variations of immune microenvironment in COPD patients, we constructed and validated a novel macrophage M0-associated diagnostic model with satisfactory predictive value. CLEC5A, FTL and SLC2A3 are expected to be promising targets of immunotherapy in COPD.

Keyphrases

chronic obstructive pulmonary disease
lung function
end stage renal disease
adipose tissue
ejection fraction
newly diagnosed
chronic kidney disease
stem cells
peritoneal dialysis
prognostic factors
genome wide
wastewater treatment
cystic fibrosis
gene expression
patient reported outcomes
patient reported