Paraneoplastic cochleovestibulopathy: clinical presentations, oncological and serological associations.
Mohammad Bakri HammamiScott D Z EggersAjay A MadhavanMayra J MontalvoSean J PittockDivyanshu DubeyPublished in: Journal of neurology, neurosurgery, and psychiatry (2021)
Cochleovestibulopathy commonly presents with rapidly progressive bilateral hearing loss and/or acute vertigo. However, in some patients, these symptoms present along with or following brainstem/cerebellar manifestations. KLHL11-IgG and seminoma are the most common serological and cancer associations, respectively. Recognition of this phenotype may aid in earlier diagnosis of paraneoplastic autoimmunity and associated cancer.
Keyphrases
- papillary thyroid
- end stage renal disease
- squamous cell
- chronic kidney disease
- newly diagnosed
- hearing loss
- ejection fraction
- multiple sclerosis
- liver failure
- prognostic factors
- respiratory failure
- patient reported
- hepatitis b virus
- extracorporeal membrane oxygenation
- robot assisted
- aortic dissection
- celiac disease