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Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population.

Toshihiro KishikawaYuichi MaedaTakuro NiiDaisuke MotookaYuki MatsumotoMasato MatsushitaHidetoshi MatsuokaMaiko YoshimuraShoji KawadaSatoru TeshigawaraEri OguroYasutaka OkitaKeisuke KawamotoShinji HigaToru HiranoMasashi NarazakiAtsushi OgataYukihiko SaekiShota NakamuraHidenori InoharaAtsushi KumanogohKiyoshi TakedaYukinori Okada
Published in: Annals of the rheumatic diseases (2019)
Our shotgun sequencing-based MWAS highlights a novel link among the gut microbiome, host genome and pathology of RA, which contributes to our understanding of the microbiome's role in RA aetiology.
Keyphrases
  • rheumatoid arthritis
  • disease activity
  • single cell
  • ankylosing spondylitis
  • interstitial lung disease
  • systemic lupus erythematosus