Long-term analysis of the benefit of prophylaxis for adult patients with severe or moderate haemophilia A.

Wolfgang A Miesbach Sabine KittlerArtur BauhoferChristoph KönigsThomas BeckerLászló NemesAlexander StausJörg Schüttrumpf

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2020)

Any (even low-frequency) prophylaxis results in lower ABR than on-demand treatment. Patients switching to prophylaxis benefitted the most, irrespective of age or HA severity. Prophylactic treatment-even tertiary-is the regimen of choice for patients of any age, including elderly patients, with severe or non-severe HA.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
early onset
prognostic factors
patient reported outcomes
combination therapy