Multipotent adult progenitor cells grown under xenobiotic-free conditions support vascularization during wound healing.

Bart VaesEllen Van HoutvenEllen CaluwéAernout Luttun

Published in: Stem cell research & therapy (2020)

Here, we demonstrated that the administration of clinical-grade XF-hMAPC cells in mice represents an effective approach for improving wound vascularization and healing that is readily applicable for translation in humans.

Keyphrases

wound healing
induced apoptosis
cell cycle arrest
tissue engineering
high fat diet induced
cell death
signaling pathway
oxidative stress
adipose tissue