PTEN regulates invasiveness in pancreatic neuroendocrine tumors through DUSP19-mediated VEGFR3 dephosphorylation.

Tsung-Ming ChangPei-Yi ChuHui-You LinKuo-Wei HuangWen-Chun HungYan-Shen ShanLi-Tzong ChenHui-Jen Tsai

Published in: Journal of biomedical science (2022)

PTEN regulates pNET invasiveness via DUSP19-mediated VEGFR3 dephosphorylation. VEGFR3 and DUSP19 are potential therapeutic targets for pNET treatment.

Keyphrases

neuroendocrine tumors
vascular endothelial growth factor
cell proliferation
pi k akt
human health
combination therapy