Model-based assessment of the safety of community interventions with primaquine in sub-Saharan Africa.
Stijn W van BeekElin M SvenssonAlfred B TionoJoseph OkebeUmberto D'AlessandroBronner P GonçalvesTeun BousemaChris DrakeleyRob Ter HeinePublished in: Parasites & vectors (2021)
This study supports the feasibility of MDA with SLD-PQ in a sub-Saharan African setting by predicting small and transient reductions in hemoglobin levels. In a setting where a substantial proportion of the population had low hemoglobin concentrations, our simulations suggest treatment with SLD-PQ would result in small increases in the prevalence of anemia which would most likely be transient.