Patterns of Anti-Seizure Medication Utilization in the Human Epilepsy Project (HEP).

Slightly more than one-third of focal epilepsy patients remain on monotherapy with their first prescribed ASM. Approximately three-in-five patients transition to monotherapy with another ASM while approximately two-in-five end up on polytherapy. Patients remain on lamotrigine for a longer duration of time compared to levetiracetam when prescribed as the initial monotherapy.