Association between kinetic of Anti-Neutrophil Cytoplasmic Antibody (ANCA), renal survival and relapse risk in ANCA-glomerulonephritis.
Clément SamoreauGiorgina Barbara PiccoliCécile MartinPhilippe GataultEmeline VinatierFrank BridouxJérémie RiouAlice DesouchePierre JourdainJean-Philippe CoindreSamuel WacrenierFanny GuibertNicolas HenryOdile BlanchetAnne CrouéAssia DjemaLise-Marie PouteauMarie-Christine CopinCéline BeauvillainJean-François SubraJean François AugustoBenoît BrillandPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2022)
ANCA kinetic after ANCA-GN diagnosis is associated with outcomes. MPO-ANCA recurrence/persistence identifies patients with a lower potential of renal recovery and a higher risk of kidney failure, while PR3-ANCA recurrence/persistence identifies patients with a greater relapse risk. Thus, ANCA kinetic may help identify patients with a smoldering disease.