Clinical and laboratory characteristics during a 1-year follow-up in European Lyme neuroborreliosis: A prospective cohort study.
Anne Marit SolheimIngerid SkarsteinHanne QuarstenÅslaug Rudjord LorentzenPål Berg-HansenRandi EikelandHarald ReisoÅse MyglandUnn LjøstadPublished in: European journal of neurology (2024)
LNB can present with solely subjective symptoms, especially pain. Many LNB patients have persistent Bb antibodies in serum and CSF. In seronegative LNB, CSF Bb-PCR and CXCL13 may give diagnostic support. CXCL13 may be persistently positive after treatment in some patients. Most of the clinical improvement occurs during the first 10 weeks. High initial clinical score is associated with poorer outcome.