Clinically Relevant Circulating Protein Biomarkers for Type 1 Diabetes: Evidence From a Two-Sample Mendelian Randomization Study.

Nahid YazdanpanahMojgan YazdanpanahYe WangVincenzo ForgettaMichael PollakConstantin Polychronakos John Brent Richards Despoina Manousaki

Published in: Diabetes care (2021)

We identified three novel circulating protein biomarkers associated with type 1 diabetes risk using an MR approach. These biomarkers are promising targets for development of drugs and/or of screening tools for early prediction of type 1 diabetes.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
insulin resistance
magnetic resonance
binding protein
magnetic resonance imaging
computed tomography
adipose tissue
contrast enhanced
skeletal muscle
small molecule