Mycobacterium tuberculosis induces host autophagic ferritin degradation for enhanced iron bioavailability and bacterial growth.

Youchao DaiChuanzhi ZhuWei XiaoXinchun ChenYi Cai

Published in: Autophagy (2023)

; TB, tuberculosis; NCOA4, nuclear receptor coactivator 4; p38, p38 protein kinase; AKT1, AKT serine/threonine kinase 1; TRIM21, tripartite motif containing 21; FTH1, ferritin heavy chain 1; FTL, ferritin light chain; HERC2, HECT and RLD domain containing E3 ubiquitin protein ligase 2.

Keyphrases

protein kinase
mycobacterium tuberculosis
iron deficiency
signaling pathway
pulmonary tuberculosis
cell proliferation
cell death
small molecule
binding protein
protein protein
emergency department
hiv aids
tyrosine kinase
electronic health record
antiretroviral therapy