Study protocol for NCCH1908 (UPFRONT-trial): a prospective clinical trial to evaluate the feasibility and utility of comprehensive genomic profiling prior to the initial systemic treatment in advanced solid tumour patients.

Takaaki MizunoTatsuya YoshidaKuniko SunamiTakafumi KoyamaNatsuko OkitaTakashi KuboKazuki SudoTatsunori ShimoiHideki UenoEiko SaitoKota KatanodaTaro ShibataKan YonemoriTakuji OkusakaNarikazu BokuYuichiro OheYukihiko HiroshimaMakoto UenoYasutoshi KubokiToshihiko DoiKenichi NakamuraTakashi KohnoYasushi YatabeNoboru Yamamoto

Published in: Japanese journal of clinical oncology (2021)

This study, initiated in June 2020, has been registered in the UMIN Clinical Trials Registry (www.umin.ac.jp/ctr/) (registration number: UMIN000040743). We plan to enrol a total of 200 patients over a period of 21 months.

Keyphrases

clinical trial
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
study protocol
open label