A novel biguanide (IM1761065) inhibits bioenergetics of glioblastoma tumorspheres.

Tae Hoon RohJi-Hyun LeeSeo Jin KimJin-Kyoung ShimJunseong Park Seon Jin YoonWan-Yee TeoSe-Hoon Kim Jong Hee Chang Seok-Gu Kang

Published in: Journal of neuro-oncology (2021)

IM1761065 is a potent inhibitor of oxidative phosphorylation. The inhibitory effect of IM1761065 on the bioenergetics of GBM-TS suggests that this novel compound could be used as a new drug for the treatment of GBM.

Keyphrases

emergency department
combination therapy
anti inflammatory
adverse drug
drug induced