Efficacy of mTOR Inhibitors and Intravenous Immunoglobulin for Treatment of Polyoma BK Nephropathy in Kidney Transplant Recipients: A Biopsy-Proven Study.
Murat KaratasErhan TatarGokalp OkutAli Murat YildirimEmre KocabasFunda Tasli AlkanCenk SimsekSait Murat DoganAdam UsluPublished in: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation (2024)
In patients with polyoma BK virus nephropathy, clearance of viremia and SV40 should not be the sole outcomes to obtain. Aggressive reductions in maintenance immunosuppression and switching to double-drug therapy combined with high-dose intravenous immunoglobulin leads to high rates of graft loss/rejection and sequalae of chronic histological changes.