Elevated T cell repertoire diversity is associated with progression of lung squamous cell premalignant lesions.
Asaf MaozCarter MerensteinYusuke KogaAustin PotterAdam C GowerGang LiuSherry ZhangHanqiao LiuChristopher StevensonAvrum SpiraMary E ReidJoshua D CampbellSarah A MazzilliMarc E LenburgJennifer E Beane-EbelPublished in: Journal for immunotherapy of cancer (2022)
Decreased TCR diversity may reflect nascent immune responses that contribute to PML elimination. Further studies are needed to explore the potential for immunoprevention of PMLs.