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Association of Insulin Dose, Cardiometabolic Risk Factors, and Cardiovascular Disease in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study.

Barbara H BraffettSamuel Dagogo-JackIonut BebuWilliam I SivitzMary LarkinOrville KoltermanJohn M Lachinnull null
Published in: Diabetes care (2019)
During DCCT/EDIC, higher insulin doses were associated with adverse trends in several cardiometabolic risk factors, even after multivariable adjustment, but not with incident CVD outcomes.
Keyphrases
  • type diabetes
  • risk factors
  • cardiovascular disease
  • glycemic control
  • insulin resistance
  • adipose tissue
  • cardiovascular risk factors
  • weight loss
  • skeletal muscle