A Systematic Review and Meta-analysis of Animal Studies Investigating the Relationship Between Serum Antibody, T Lymphocytes, and Respiratory Syncytial Virus Disease.

Joseph McGinleyRyan ThwaitesWill BrebnerLewis Greenan-BarrettJeroen AerssensDeniz ÖnerLouis BontJoanne WildenbeestFederico Martinón-TorresHarish NairAndrew J PollardPeter OpenshawSimon Drysdalenull null

Published in: The Journal of infectious diseases (2021)

Murine studies suggest that measures of T-lymphocyte activity (particularly CD4 and CD8 T cells) may be predictive biomarkers of severity. Further inquiry is merited to validate these results and assess relevance as biomarkers for human disease.

Keyphrases

respiratory syncytial virus
endothelial cells
case control
induced pluripotent stem cells
peripheral blood