Efficient Synthetic Routes to (±)-Hippolachnin A, (±)-Gracilioethers E and F and the Alleged Structure of (±)-Gracilioether I.
Ze-Jun XuYikang WuPublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2017)
Two monocyclic members in the gracilioether family were synthesized in only three steps. The monocyclic products were further elaborated into advanced precursors to hippolachnin A and gracilioether E, respectively. Gracilioether F and the alleged structure for gracilioether I were also synthesized using a late-stage C(sp3 )-H thermo-oxidation.