Saffron and Its Major Ingredients' Effect on Colon Cancer Cells with Mismatch Repair Deficiency and Microsatellite Instability.

Amr AminAaminah FarrukhChandraprabha MuraliAkbar SoleimaniFrançoise Praz Grazia GrazianiHassan BrimHassan Ashktorab

Published in: Molecules (Basel, Switzerland) (2021)

Saffron's anti-proliferative effect is significant in cells with deficient MMR. This novel effect may have therapeutic implications and benefits for MSI CRC patients who are generally not recommended for the 5-fluorouracil-based treatment.

Keyphrases

end stage renal disease
chronic kidney disease
induced apoptosis
ejection fraction
peritoneal dialysis
newly diagnosed
replacement therapy
cell proliferation
patient reported outcomes
smoking cessation
patient reported
wild type