In vivo Targeting of Liver Cancer with Tissue- and Nuclei-Specific Mesoporous Silica Nanoparticle-Based Nanocarriers in mice.

Ziqiang DingDujin WangWei ShiXiaomei YangSiliang DuanFengzhen MoXiaoqiong HouAiqun LiuXiaoling Lu

Published in: International journal of nanomedicine (2020)

TLS11a-LB@TATp-MSN/DOX can efficiently deliver DOX to the nuclei of liver cancer cells by dual targeting liver cancer tissue and the nuclei of the cancer cells in mice. Thus, it is a promising nano-drug for the treatment of liver cancer.

Keyphrases

cancer therapy
high fat diet induced
drug delivery
type diabetes
emergency department
adipose tissue
combination therapy
drug release
skeletal muscle