Fire Needling Acupuncture Suppresses Cartilage Damage by Mediating Macrophage Polarization in Mice with Knee Osteoarthritis.

Jiangyan WeiLu LiuZhijuan LiTianli LyuLuo-Peng ZhaoXiaobai XuYine SongYidan DaiBin Li

Published in: Journal of pain research (2022)

Fire needling acupuncture decreases pain behaviors in KOA mice and improves synovial membrane injury and pathological cartilage damage. The macrophage polarization is involved in the mechanism of fire needling acupuncture's amelioration of articular cartilage damage.

Keyphrases

knee osteoarthritis
oxidative stress
high fat diet induced
chronic pain
extracellular matrix
pain management
insulin resistance
wild type
metabolic syndrome
skeletal muscle