Compensated Hypogonadism Identified in Males with Cluster Headache: A Prospective Case-Controlled Study.
Anja Sofie PetersenDavid M KristensenConnar Stanley James WestgateThomas Folkmann HansenNunu LundMads BarloeseMarie-Louise K SøborgAgneta SnoerTrine H JohannsenHanne FrederiksenAnders JuulRigmor H JensenPublished in: Annals of neurology (2024)
Our results demonstrate that the male endocrine system is altered in patients with cluster headache to a state of compensated hypogonadism, and this is not an epiphenomenon associated with sleep or the use of acute medication. Together with the identified shared genetic risk allele, this may suggest a pathophysiological link between cluster headache and fT. ANN NEUROL 2024.