Obtaining patient phenotypes in SARS-CoV-2 pneumonia, and their association with clinical severity and mortality.
Fernando García-GarcíaDae-Jin LeeMónica Nieves-ErmecheoOlaia BrontePedro Pablo EspañaJosé María QuintanaRosario MenéndezAntoni TorresLuis Alberto Ruiz IturriagaIsabel Urrutianull nullPublished in: Pneumonia (Nathan Qld.) (2024)
A compound unsupervised clustering technique (including a fully-automated optimization of its internal parameters) revealed the existence of three distinct groups of patients - phenotypes. In turn, these showed strong associations with the clinical severity in the progression of pneumonia, and with mortality.
Keyphrases
- sars cov
- end stage renal disease
- cardiovascular events
- ejection fraction
- chronic kidney disease
- single cell
- newly diagnosed
- prognostic factors
- high throughput
- peritoneal dialysis
- case report
- type diabetes
- intensive care unit
- sensitive detection
- rna seq
- coronary artery disease
- fluorescent probe
- living cells
- respiratory failure
- patient reported