Effect of incubation with crystalloid solutions or medications on packed red blood cells.
Domagoj MladinovKristine YarnoffEnika NagababuDaniel E BerkowitzCourtney LawrencePaul M NessThomas KicklerPatricia A BrunkerJoan S BoydJeffrey M Dodd-OPublished in: Transfusion (2019)
Our data suggest that 5 minutes of PRBC incubation with isotonic crystalloids or catecholamines does not deleteriously alter PRBC hemolysis, membrane deformability, or aggregation. Co-incubation with D5W likely increases hemolysis. Propofol may promote hemolysis.