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Neoadjuvant Cemiplimab for Stage II to IV Cutaneous Squamous-Cell Carcinoma.

Neil D GrossDavid Michael MillerNikhil I KhushalaniVasu DiviEmily S RuizEvan J LipsonFriedegund MeierYungpo B SuPaul L SwiecickiJennifer AtlasJessica L GeigerAxel HauschildJennifer H ChoeBrett G M HughesDirk SchadendorfVishal A PatelJade HomsiJanis M TaubeAnnette M LimRenata FerrarottoHoward L KaufmanFrank SeebachIsrael LowySuk-Young YooMelissa MathiasKeilah FenechHyunsil HanMatthew G FuryDanny Rischin
Published in: The New England journal of medicine (2022)
Neoadjuvant therapy with cemiplimab was associated with a pathological complete response in a high percentage of patients with resectable cutaneous squamous-cell carcinoma. (Funded by Regeneron Pharmaceuticals and Sanofi; ClinicalTrials.gov number, NCT04154943.).
Keyphrases
  • locally advanced
  • squamous cell carcinoma
  • rectal cancer
  • radiation therapy
  • lymph node
  • lymph node metastasis
  • mesenchymal stem cells
  • replacement therapy