Postoperative complications and oncologic outcomes after multimodal therapy of localized high risk soft tissue sarcoma.
Vlatko PotkrajcicJonas KolbenschlagSaskia SachsenmaierAdrien DaigelerRuth LadurnerAlexander GolfCihan GaniDaniel ZipsFrank PaulsenFranziska EckertPublished in: Radiation oncology (London, England) (2022)
Rates of major wound complications in this cohort are comparable to published data, higher rates of wound infections were observed after neoadjuvant radiotherapy. Tumor localization, patient age and diabetes seem to be major risk factors. The number of risk factors for high risk soft tissue sarcoma seem to influence DMFS. Neoadjuvant treatment increases the risk only for wound infection treated with oral or intravenous antibiotic therapy and appears to be a safe option at an experienced tertiary center in absence of other risk factors.
Keyphrases
- risk factors
- rectal cancer
- locally advanced
- lymph node
- type diabetes
- surgical site infection
- wound healing
- early stage
- radiation therapy
- case report
- stem cells
- electronic health record
- pain management
- machine learning
- metabolic syndrome
- adipose tissue
- glycemic control
- low dose
- mesenchymal stem cells
- deep learning
- artificial intelligence
- bone marrow
- chronic pain
- insulin resistance
- data analysis