Repositioning antispasmodic drug Papaverine for the treatment of chronic myeloid leukemia.
Phani Krishna ParchaSailu SarvagallaCheemala AshokS J SudharshanMadhu DyavaiahMohane Selvaraj CoumarBaskaran RajasekaranPublished in: Pharmacological reports : PR (2021)
The data presented here have added support to the concept of polypharmacology of existing drugs and natural compounds to interact with more than one target. This study provides a proof-of-concept for repositioning Papaverine as an anti-CML drug.