Leukocyte Telomere Length and Mitochondrial DNA Copy Number in Treatment-Resistant Depression and Response to Electroconvulsive Therapy: A Pilot Longitudinal Study.

Alessio SquassinaClaudia PisanuValentina MeneselloAnna MeloniDonatella CongiuMirko ManchiaPasquale ParibelloMaria AbateMarco BortolomasiBernhard T BauneMassimo GennarelliAlessandra Minelli

Published in: The journal of ECT (2024)

Ours is the first longitudinal study exploring the role of LTL and mtDNA-cn in response to ECT. Findings of this pilot investigation suggest that LTL and mtDNA-cn may constitute disease biomarkers for TRD but are not involved in response to ECT.

Keyphrases

mitochondrial dna
copy number
lymph node metastasis
genome wide
study protocol
dna methylation
peripheral blood
sleep quality
squamous cell carcinoma
gene expression