Correlation of immediate prevalence of cervical precancers and cancers with HPV genotype and age in women with ASC-US/hrHPV+: a retrospective analysis of 2292 cases.

Qin LiuTao ZhangLiqing ChenXin ZhouXiaofei ZhangWenxin ZhengShuang NiuFeng Zhou

Published in: Journal of clinical pathology (2023)

Women with ASC-US/hrHPV+ are at significant risk of cervical precancers and cancers; notably, HPV-16+ group has a higher risk of HSIL squamous lesions and SCC while HPV-18/45+ group has a higher risk of AIS+ glandular lesions. In addition, the older patient group (>50 years) has a significantly higher risk of SCC. Therefore, HPV genotyping as well as patient age need to be considered in the clinical management of patient.

Keyphrases

high grade
case report
low grade
cervical cancer screening
risk factors
nlrp inflammasome
gene expression
middle aged