Cognitive Impairment in Tuberculous Meningitis.
Angharad G DavisAnna J DreyerChristine AlbertynMpumi MaxebengulaCari StekSean WassermanSuzaan MaraisKathleen BatemanMark SolmsJohn JoskaRobert J WilkinsonSam NightingalePublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Low cognitive performance following HIV-associated TBM is common. This effect is independent of, and additional to, effects of HIV and non-CNS TB disease. Further studies are needed to understand longer term outcomes, clarify the association with treatment adherence, a key predictor of outcome in TBM, and develop context-specific tools to identify individuals with cognitive difficulties to improve outcomes in TBM.