Somatic mutation contributing to clonal haematopoiesis is a risk factor of recurrent stroke in first-ever acute ischaemic stroke: a prospective cohort study.
Xin QiuYalun DaiSi ChengHong-Qiu GuYong JiangXia MengYilong WangXing-Quan ZhaoYingyu JiangZhe XuXinying HuangMeng WangTian Jie LyuYubo WangJiaxu WengLingyun CuiYi ShangguanHao LiYongjun WangZi-Xiao LiPublished in: Stroke and vascular neurology (2022)
Our results suggest that somatic mutations contributing to CHIP increase the risk of short-term recurrent stroke in patients who had a first-ever AIS. Hyperinflammation may be important in the relationship between CHIP and recurrent stroke.