Characterization of bioactive substances involved in the induction of bone augmentation using demineralized bone sheets.

Haruka SaitoRisako Chiba-OhkumaYasuo YamakoshiTakeo KarakidaRyuji YamamotoMai ShiraiChikahiro Ohkubo

Published in: International journal of implant dentistry (2022)

Demineralized bone sheets are capable of inducing bone augmentation, and this ability is mainly due to TGF-β in the bone protein mixed with the sheets. The activity of TGF-β is maintained when binding to bone NCPs such as DMP1, MEPE, and BGN in the sheets.

Keyphrases

bone mineral density
soft tissue
bone loss
bone regeneration
epithelial mesenchymal transition