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Sericin-mediated improvement of dysmorphic cardiac mitochondria from hypercholesterolaemia is associated with maintaining mitochondrial dynamics, energy production, and mitochondrial structure.

Kitiya RujimongkonSumate AmpawongDuangnate IsarangkulOnrapak ReamtongPornanong Aramwit
Published in: Pharmaceutical biology (2022)
Sericin treatment could improve the dysmorphic mitochondrial structure, metabolism, and energy production of cardiac mitochondria under hypercholesterolaemia. These results suggest that sericin may be an alternative treatment molecule that is related to cardiac mitochondrial abnormalities.
Keyphrases
  • oxidative stress
  • left ventricular
  • cell death
  • heart failure
  • combination therapy
  • smoking cessation